BioDynaMo

Modelling tomorrow, today

Agent-based modelling (ABM) is a powerful methodology for studying complex systems in biology, epidemiology, economics, social sciences, medicine and many other fields.

Biology Dynamics Modeller (BioDynaMo) is ABM software capable of simulating the behaviour of complex systems, such as neural development, tumour growth and cell migration. During the coronavirus pandemic, it was even used to simulate the spread of the SARS-CoV-2 virus.

Being open source, BioDynaMo can be downloaded and used free of charge by anyone around the world.

So how could it be used to benefit society?

Cancer: BioDynaMo can simulate cancer growth and treatment responses in 3D, enabling the development of personalised treatment plans and reducing side effects by modelling interactions between cancer cells, immune cells, healthy cells, diffusing substances, etc.

Dengue: The platform helps simulate mosquito populations and disease transmission dynamics, taking into account environmental, immunological and behavioural factors, to support dengue control and elimination strategies in urban areas.

Inequality: BioDynaMo assists governments in urban planning and socio-economic decision-making by modelling scenarios aimed at addressing and reducing socio-economic inequalities, thereby promoting more resilient societies.

As an innovative means of supporting both research and education, we can further improve and develop BioDynaMo’s capabilities through external donations.

Check out some of the simulations made using BioDynaMo:

Cortical Neuron Growth Simulation

Lukas Breitwieser et al

Alveolar Structure

Source: Dr Nicolò Cogno

Soma Group Clustering Simulation

Lukas Breitwieser et al

Cortical Neuron Growth Simulation

Lukas Breitwieser et al

Alveolar Structure

Source: Dr Nicolò Cogno